How long should you store Otofa after opening the bottle?

Otipax is a French-made drug that is widely used to treat inflammatory processes in the auricle. The advantage of the drug is the possibility of its use by both adults and children from the first days of life and pregnant women. Many doctors classify Otipax as a first aid drug for inflammatory otolaryngological diseases that are accompanied by acute ear pain. Considering that this drug can be used by children, pediatricians often recommend having Otipax in your home medicine cabinet, since ear pain in children is quite common, and more often at night, when it is not possible to see a doctor. Otipax is also popular among adults, since its use will help get rid of various inflammatory processes in the ears. Otipax drops can be used to relieve pain, as well as in combination with other drugs for symptomatic therapy.

Description of the drug

Otipax is a combined local drug with a powerful anti-inflammatory and analgesic effect, which is used to treat otitis media accompanied by severe ear pain. The advantage of the drug is its good tolerability, rapid effect, absence of pronounced contraindications and side effects. The only exception to the use of this remedy is damage to the eardrum. After instillation, Otipax begins to act within 5 minutes, and acute pain in the ear will completely disappear within 15 to 25 minutes after instillation. The active components of the drug are lidocaine and phenazone, as well as auxiliary components. The combination of two components in the drug allows it to act quickly enough, have a positive effect on the inflammatory processes occurring in the auricle, relieve ear pain, thereby improving the general condition of a person.

Otipax ear drops are available in a glass bottle with a dispenser. The manufacturer of this drug is France. The drops have a transparent substance with a yellowish tint and the smell of alcohol.

How long is Otipax good for after opening?

Instructions for use Before using the drug, you need to make sure that the patient's eardrum is not damaged. Therefore, it is best if Otipax is prescribed by a doctor. The specialist will also determine the required dosage depending on the severity of the patient’s condition. Usually drops are instilled into each ear.

This treatment procedure should be performed 2 or 3 times a day. The duration of therapy depends on the patient’s condition; most often it is recommended to continue therapy for at least 10 days. After all, the anti-inflammatory effect begins to appear only a couple of days after the start of treatment. Otipax can be instilled once only for short-term pain relief after injury or removal of a foreign body.

otitis media in the acute period at the time of inflammation; otitis media as a complication after influenza; barotraumatic edema. With caution It is necessary to ensure the integrity of the eardrum before starting to use the drug. If the drug is used with a perforated eardrum, the drug may come into contact with the organs of the middle ear and lead to complications.

Information for athletes: the drug contains an active component that can give a positive reaction during doping control. Use during pregnancy and breastfeeding There are no restrictions on the use of the drug during pregnancy and breastfeeding, provided the eardrum is intact.

Add to favorites Otipax - instructions for use, reviews, analogues and release forms of ear drops for the treatment of otitis media and ear pain in adults, children and pregnancy. Expiration date after opening the bottle In this article you can read the instructions for use of the drug Otipax.

Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Otipax in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation.

Otipax analogues in the presence of existing structural analogues. Use for the treatment of otitis media and ear pain in adults, children, as well as during pregnancy and breastfeeding. Expiration date after opening the bottle of ear drops. Otipax is a combination drug for topical use.

Lidocaine is a local anesthetic. The combination of phenazone and lidocaine promotes a faster onset of anesthesia, and also increases its intensity and duration.

Hypersensitivity to the active substances, any components of the drug or to amide local anesthetic drugs. Perforation of the eardrum of traumatic or infectious origin, see Interaction with other drugs and other types of interactions. Currently, there is no data on the possibility of clinically significant interactions.

Features of use Before any use of the drug, the integrity of the eardrum should be checked as a preventive measure. If there is destruction of the eardrum, injection of the drug into the ear may cause the drug to come into contact with the structures of the middle ear, causing adverse reactions in these tissues.

It should be taken into account that the drug contains an active component that can show a positive result in an anti-doping test. Use during pregnancy or breastfeeding There are no expected consequences of using the drug during pregnancy, since the systemic exposure of phenazone and lidocaine is insignificant.

Contraindications: hypersensitivity to choline salicylate or other components of the drug; complete or incomplete combination of bronchial asthma, recurrent polyposis of the nose and paranasal sinuses and intolerance to acetylsalicylic acid or other NSAIDs, including. With caution: allergic hay runny nose, polyps of the mucous membrane of the nasal passages.

Use during pregnancy and breastfeeding Use of the drug during pregnancy and in nursing mothers is contraindicated due to the lack of appropriate studies. Side effects Local hypersensitivity reactions: itching, redness of the skin. If the patient experiences side effects indicated in the instructions, or they get worse, or any other side effects not listed in the instructions are noticed, you should inform your doctor.


Otipax ear drops contain two active ingredients - phenazone (40%) and lidocaine hydrochloride (10%), as well as auxiliary components, including glycerol, ethyl alcohol, sodium thiosulfate and water.

Phenazone is a component with anti-inflammatory and analgesic effects. This substance is also included in other medications, therefore it is widely used in the pharmacological production of drugs that reduce elevated body temperature. Phenazone belongs to the group of pyrazolones, is well tolerated by the body, and has virtually no contraindications. A few years ago, this component was used as an antipyretic and hemostatic agent, but today it is practically not used as an independent drug.

Lidocaine is a local anesthetic drug with a pronounced analgesic effect. It is quite widely used in medicine to relieve pain, does not affect the neurons of the brain, and acts within 2 hours.

The combination of two active components in the composition of Otipax ear drops allows you to enhance the effect of each other, thereby creating a powerful remedy for the treatment of the inflammatory process in the auricle.

Interaction with other medications

Auxiliary components in Otofa drops:

  • Macrogol 400 is an auxiliary chemical substance, the basis for various dosage forms;
  • Nartia edetate – preservative;
  • lithium hydroxide – food preservative;
  • potassium metabisulfite – food additive, medicinal filler;
  • ascorbic acid;
  • purified water.

It is strictly forbidden to use Otipax if the integrity of the eardrum is damaged, as well as if there is an individual intolerance to the components that are included in the composition.

The drug contains 2.6 grams of rifamycin sodium. This is an antibiotic from the rifampicin group. It fights harmful microorganisms that cause ear infections. In addition to the main component, the drug contains: active potassium disulfite, lithium hydroxide, disodium edetate, concentrated ascorbic acid, water, macrogol 400.

Otipax is a drug for topical use. The active ingredients of this medication are phenazone and lidocaine. The drug is produced in tinted glass bottles, which are equipped with a dropper. Each bottle is packed in a cardboard box along with instructions for use. The shelf life of a medicinal product whose packaging is not damaged is 5 years.

Successful relief from ear diseases is impossible without drugs with bactericidal and antibacterial effects. Otof drops are known in otorhinolaryngology due to their effectiveness and low price.

The instructions for Otipax note that the drug is intended to relieve pain and inflammation in the ear canal. Thanks to their special composition, these drops not only help eliminate swelling, redness, itching and pain, but also fight the cause of the inflammatory process. Therefore, Otipax is most often used for otitis media of any origin as part of complex treatment.

Pharmacological properties

Otipax is a local drug, widely used in ENT practice by doctors to relieve pain and eliminate the inflammatory process in the auricle. It is recommended to be used for local symptomatic treatment, as an analgesic and anti-inflammatory agent for adults and children of all ages, including newborns.

The drug has a pronounced anti-inflammatory and analgesic effect. As the instructions for Otipax indicate, it does not damage the eardrum, practically does not penetrate the bloodstream, and acts only at the site of inflammation. Thanks to the balanced composition of the drug, it quickly relieves pain and inflammation, but does not eliminate the cause, so even after using this drug, you need to consult an otolaryngologist.

Consequences of using expired drops

Having analyzed the reviews on the drug in question, we can conclude that those drops that were opened more than 6 months ago are also suitable for use. However, to protect your health, it is better not to use the substance after 6 months from the date the package was opened. Such drops may not only not have a positive effect on relieving unpleasant symptoms, but also cause harm to the body. If you open the bottle, the sterility is broken, but the effectiveness of the product is still active for a year. In order for the medicinal substance to remain as productive for a long time, it is recommended to maintain the storage temperature.

When an inflammatory process in the ear begins, it is acceptable to use the drug Otipax, which was used earlier, but was stored in the refrigerator. If the eardrum is damaged, the drug does not enter the bloodstream and acts locally. Accordingly, it does not cause any harm. When using drops that were stored in violation of the recommended temperature exposure, two scenarios are possible:

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1. Otipax will not help relieve painful symptoms (in this case, you should purchase a new drug). 2. The pain in the ears will soon subside, which means that the medicine has retained its properties.

The manufacturing company sells the drug Otipax in 15-16 ml containers. This amount of product is enough for repeated use. If the drug is not needed, it is placed in the refrigerator door.

Do not use drops if there is a risk of perforation of the eardrum.

The effect of the drug Otipax gives an anti-inflammatory and anesthetic effect. The drug is used when it is necessary to treat otitis media and other similar ear diseases and inflammations. The recovery process most often takes about 10 days. In the future, a large number of patients think about the issue of safe and effective storage of the drug in question. The instructions say that after the sterility of the packaging has been compromised, the bottle of medicine can be stored for no more than 6 months. Also, storage conditions have a significant impact on the quality of the drug.

It is advisable to keep ear drops in the refrigerator throughout the entire treatment, but before use, for more comfortable use, you can warm the bottle in your palms for several minutes to a temperature of about 20 degrees.

Indications for use

Otipax ear drops can be used for the following diseases of the auricle:

  1. Serous acute or chronic otitis media of the middle ear.
  2. Ear pain with non-suppurative otitis media.
  3. Otitis externa.
  4. Acute otitis.
  5. Ear pain due to acute viral respiratory infection.
  6. Abscess of the external auditory canal.
  7. Paratraumatic otitis.
  8. Anti-influenza otitis.

For external or other otitis, it is important to use Otipax drops as early as possible, this way you can avoid all sorts of complications that appear against the background of acute inflammation in the auricle. You can use ear drops during a cold or flu, especially when a person feels fullness, ringing or pain in the ears against the background of a viral infection. This drug is often used to treat paratraumatic otitis media, which occurs against the background of high blood pressure. This condition is typical for people involved in swimming and diving, since this type of otitis occurs more often after diving to a depth of 2 meters.

It is important to note that when ear pain occurs that is not caused by a purulent inflammatory process, Otipax drops are the most effective because they can relieve a person of painful ear pain after just a few minutes of use.

Mode of application

Otipax drops are easy to use because they have a dropper - a dispenser.

In case of inflammation in the auricle, adults are recommended to instill 4 drops of the drug 2 – 3 times. During the instillation process, you need to tilt your head slightly to the side. After instillation, you can put a cotton swab in your ear. Drops should be instilled into both the diseased and healthy ear, since there is always a risk of inflammation spreading to the healthy ear canal. The course of treatment is from 5 to 10 days. Before using the drug, you need to hold it in your hand for a few minutes or dip the bottle in warm water. The therapeutic effect will be noticeable after the first use of the medicine.

Instructions for use

Otofa can be used by people of any age, as well as newborns, pregnant and nursing mothers. The shelf life of the medicine after opening the bottle is six months. Ear drops are instilled with a pipette with a dispenser into the ear, five drops two to three times a day for patients over twelve years of age. For otitis in children under 12 years of age, drops are administered three times a day.

How to administer drops correctly:

  1. Warm the drops in your palms to room temperature.
  2. If the baby is excited, then ask someone to help.
  3. Wash your hands and place the newborn on his side so that the sore ear is on top.
  4. Carefully clean the ear of wax and discharge.
  5. Pipette the drug.
  6. Pull the auricle back and down to align the ear canal.
  7. After administering the drops, place a cotton swab outside and leave it for a while.
  8. The pipette is inserted half a centimeter into the child's ear.
  9. If the eardrum is perforated, an indirect method of administering the medication is used.

A cotton ball is taken, inserted into the ear canal, and the solution flows along the band to the site of inflammation. The course of treatment with Otofa is 7 days. If necessary, the doctor can extend the treatment.


Like any other drug, Otipax has some contraindications, but unlike other drugs, their list is several times lower. The following conditions are considered the main contraindications to the use of Otipax:

  1. Hypersensitivity to the composition of the drug.
  2. Damage to the eardrum.
  3. Purulent processes in the auricle.

Many pediatricians recommend that before using the drug for children prone to various forms of allergies, apply a few drops to the wrist and wait a few minutes. If there is no redness or itching in the area where the medicine is applied, then you can instill it into the auricle. During pregnancy, drops can be used, but only after consulting a doctor. Some studies have shown that the active components of the drug can partially penetrate into breast milk, so during lactation it is better to stop using drops or stop breastfeeding.

Otipax ear drops 16 ml

This combination drug is applied topically and has an anti-inflammatory and anesthetic effect. The instructions indicate that this period should not exceed six months, but it all depends on the storage conditions. Each bottle is packed in a cardboard box along with instructions for use. After opening, the shelf life is significantly reduced and, according to the instructions, is 6 months.

Skin rash. Individual intolerance to the drug is possible, so if undesirable symptoms appear, consult a doctor. During pregnancy, there are no consequences from the use of Otipax drops, since systemic exposure of lidocaine with phenazone is minimal.

If you follow the instructions, the active substances will not pass into breast milk. There is no data on the safety of using Otipax drops in the treatment of children under 1 month of age.

The drug affects the speed of nervous reactions, including when driving vehicles and other equipment. Persons working in specialized industries should exercise caution. Precautions During pregnancy, the drug is used only after consultation with the gynecologist managing the pregnancy.

As we already wrote above, before using the drug, you must make sure that the eardrum is intact; if there is damage, the active components of the drug may begin to contact the organs of the middle ear, which will cause the development of adverse reactions. Athletes should be aware that the drops contain an active component that gives a positive reaction in doping control tests.

Allergic reactions are observed in patients with hypersensitivity to the active components of the formula. How to store Otipax for children and adults is stored at a temperature of 15 to 30 degrees. Choose a place where ultraviolet radiation will not reach.

We remind you that you cannot buy the drug outside of pharmacy chains, since in this case no one can guarantee you its quality, authenticity and effectiveness. You can save money by choosing cheaper alternatives. Like any imported drug, Otipax ear drops have structural and functional analogues that are lower in cost.

Let's look at them. Analogues of Otipax ear drops for children are selected very carefully - the formula should not contain potentially dangerous components. Structural analogues have identical composition and therapeutic effect - the difference lies in the country of production and brand, there may be slight differences in excipients. Main medications: Otirelax - relieves inflammation, pain, swelling. Side effects and indications for Otirelax are the same as for Otipax.

The country of origin of Otirelax is Romania, the cost is about rubles less. Oticaine is a Ukrainian pharmaceutical drug. The composition and action are the same as Otipax, the cost does not exceed rubles. Droplex is another analogue that can also be used to treat infants. The cost is the same as Otipax drops, or slightly lower. Their cost is approximately rubles.

Analogues of Otipax for therapeutic action: Otinum is an anti-inflammatory non-steroidal drug containing choline salicylate. Used symptomatically, locally, eliminates inflammation, pain, removes sulfur plugs. Otinum is not prescribed to children and pregnant women; intolerance to salicylates is also a contraindication to therapy. The cost is almost the same as Otipax, sometimes a little lower.

Furotalgin is an anti-inflammatory, antibacterial drug, analgesic. Used for inflammation of the superficial areas of the ear canal, otitis. For otomycosis, perforation of the eardrum, individual intolerance to the active components of the drug Furotalgin is not prescribed. It can be used in pediatrics, but after 12 months.

For children, Otizol is used over the age of 6 months; during pregnancy, the drug is used only as directed by a doctor. These formulas do not contain antibacterial substances, therefore, for infectious otitis media, it is additionally recommended to use an antibiotic.

Treatment with Otipax will be most successful if antibiotics are used along with ear drops. We remind you that such drugs should be prescribed by a doctor and only if necessary. The duration of treatment with antibiotics should not be exceeded, since aggressive substances have a negative effect on the human body.

Since Anuran is an antibiotic, it is used for acute otitis media, purulent discharge from the ears, and violations of the integrity of the eardrum. Otofa is an analogue of Otipax, which is also used for ruptured eardrums.

Otofa is not often prescribed, usually at the purulent stage of otitis, when perforation of the membrane has already occurred. There are no painkillers or anti-inflammatory components in Otofa, but the drops relieve swelling, redness, and pain well.

Conclusion Otipax is an effective ear drop that is used to treat otitis media in children and adults. During pregnancy, the drug is also used, but under the supervision of a doctor.

Otipax ear drops have a number of cheaper structural, therapeutic analogues, as well as products with antibiotics. One of the most unpleasant ailments that befalls a person is ear pain. Moreover, while a runny nose and cough can be more or less somehow dealt with, pain in the ears is difficult to endure.

Yes, and this can lead to serious consequences. One of the most famous and popular drugs prescribed by doctors for ear pain is Otipax. Otipax is a fairly well-known drug that is used by ENT doctors. It contains two main active ingredients - lidocaine and phenazone, each of which performs important functions: Lidocaine is a well-known anesthetic substance that is used very widely in medicine.

True, not all people can tolerate it, as an allergic reaction may develop. As for phenazone, it is not only an anesthetic substance, but it can also relieve inflammation. Its effect on lowering body temperature is very unusual.

Due to the excellent interaction of the substances that make up the drug with each other, the effect lasts for a long time, and therefore eliminates the need to use drops frequently. Indications for use of Otipax As mentioned above, the main purpose of the drug.

These include: Intolerance to some components of the drug. This is mainly intolerance to lidocaine. Many doctors, before prescribing Otipax, ask the patient about the presence of an allergic reaction to the drug.

In this case, the use of Otipax is strictly prohibited, as it will do more harm than good. Moreover, this includes both infectious and traumatic damage to the membrane. The same applies to pregnancy, then Otipax can be prescribed only if there is no harm to the child, and if the condition of the expectant mother is so serious that it cannot be avoided.

Also, it is forbidden to use the drug while breastfeeding, since there are studies from which it can be concluded that the drug, albeit in small doses, is absorbed into the blood and milk. Athletes should use the drug with caution. Because due to the interaction of the components of the drug with each other, the results of the doping test may be positive.

That is why it is better to choose drugs with other components. Method of administration and side effects of the drug Typically, the course of treatment with drops lasts from seven to ten days. For adults, drops are allowed to be used no more than two or three times a day. Moreover, it is necessary to drip three or four drops. For the best effect.

As for newborn children, the dosage in this case is determined individually, based on the advanced state of the baby’s disease. The same can be said about older children, for whom the drug is allowed to be used, but this can only be done after a doctor has prescribed it and determined the dosage.

Due to the fact that it is better to store Otipax in the refrigerator, before using the medicine you need to warm it in your hands so that it becomes room temperature and the instillation process does not cause discomfort. One of the features of the drug, unlike others, is that after opening the bottle, it can be stored.

The main thing is to observe the temperature regime. Otipax is one of the most modern drugs that can cause minimal side effects.

Due to the fact that it acts locally, it is practically not absorbed into the blood. But all the same, if used incorrectly or used without a doctor’s prescription, that is, without observing dosages and taking into account personal characteristics, adverse reactions may occur.

More information about otitis media can be found in the video. Side effects of the drug: Allergy. As a rule, an allergic reaction occurs to lidocaine. Less often on phenazone. Hives and itching may appear. Redness of the skin inside or outside the ear. Skin irritation. Deafness, both partial and complete, which occurs if the drug is used in the presence of a damaged eardrum.

Side effects

Ear drops are well tolerated by the human body, and only in very rare cases may a slight burning or irritation be felt in the ear area after their use. Such symptoms most likely indicate the development of an allergic reaction. If you are hypersensitive to the composition of the drug, you should stop using it and consult a doctor who can select another drug.


The pharmaceutical industry offers several analogues of the drug Otipax, but it is not recommended to use them without first consulting a doctor. Otipax analogues are much cheaper, have the same composition, but are produced using completely different technologies by domestic or foreign companies. In cases where Otipax is not available, the doctor can replace it with a drug such as Otirelax or Folicap. Such drops can be used by adults and children, but only as prescribed by a doctor.

Features of application

In order to achieve a quick and lasting therapeutic effect, when using Otipax drops you need to adhere to several rules:

  1. Use the drug only as prescribed by a doctor.
  2. Strictly adhere to the dosage and course of treatment.
  3. Before instillation, warm the bottle.
  4. After instillation, lie down for a few minutes.
  5. After opening, store the drug in the refrigerator, on the bottom shelf of the door.
  6. If there is purulent discharge from the ear, do not use the medicine, as well as if you suspect damage to the eardrum.

During clinical trials, it was proven that Otipax is one of the effective fast-acting drugs that is well tolerated by the human body. In addition, the use of this drug in the first hours after the onset of otitis media will help avoid all sorts of complications, as well as the progression of the disease and its spread to the healthy ear.

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