Derinat

  • Compound
  • Description
  • pharmachologic effect
  • Pharmacokinetics
  • Indications for use
  • Contraindications
  • Pregnancy and lactation
  • Directions for use and doses
  • Side effect
  • Overdose
  • Interaction with other drugs
  • Features of application
  • Precautionary measures
  • Release form
  • Storage conditions
  • Best before date
  • Conditions for dispensing from pharmacies

pharmachologic effect

The drug activates cellular and humoral immunity. Optimizes specific responses against fungal, viral and bacterial infections. The drug stimulates reparative and regenerative processes, normalizes the condition of tissues and organs in dystrophies of vascular origin. Derinat promotes the healing of trophic ulcers of various etiologies. Derinat promotes rapid healing of deep burns, significantly accelerating the dynamics of epithelization. When ulcerative formations on the mucous membrane are restored under the influence of Derinat, scarless restoration occurs. The drug does not have teratogenic or carcinogenic effects.

Instructions for using Derinat nasal drops

Drops are instilled according to the instructions:

  1. Sit down and tilt your head back, or take a lying position.
  2. Turn your head to the left.
  3. Place 2-5 drops (depending on the purpose) into the left nasal passage.
  4. Pinch the left nostril with your finger and make several circular massaging movements so that the drug is evenly distributed throughout the mucous membrane.
  5. Turn your head to the right.
  6. Repeat steps 3-4 for the right nasal passage.

To treat a viral respiratory disease, Derinat is instilled every 1.5 hours or even more often. For preventive purposes, it is sufficient to use the drug three times a day.

Indications for use

Monotherapy:

— acute respiratory diseases (ARI):

— prevention and treatment of acute respiratory viral infections (ARVI);

— ophthalmology: inflammatory and dystrophic processes;

- inflammatory diseases of the mucous membranes of the oral cavity;

Complex therapy:

— chronic inflammatory diseases, fungal, bacterial and other infections of the mucous membranes in gynecology;

- acute and chronic diseases of the upper respiratory tract (rhinitis, sinusitis, sinusitis, frontal sinusitis);

- trophic ulcers, long-term non-healing and infected wounds (including diabetes mellitus);

- gangrene;

- burns, frostbite;

- post-radiation necrosis of the skin and mucous membranes.

Contraindications

Most often, Derinat spray and drops are prescribed for influenza or ARVI, as well as for prophylactic purposes to protect the child from colds and viral infections of the nasopharynx. In such cases, the medication can be used independently as monotherapy.

Other reasons to prescribe the drug are:

  • Inflammatory diseases of the respiratory tract, such as otitis media, pharyngitis, tonsillitis or adenoiditis. For such pathologies, Derinat is often used as one of the drugs in complex treatment, supplementing antibiotics, antivirals, antipyretics and other medications with this drug.
  • Stomatitis, gingivitis and other lesions of the oral cavity. For these pathologies, rinsing or local treatment with a spray is prescribed.
  • Ophthalmological diseases occurring with a dystrophic or inflammatory process. For conjunctivitis, barley and other diseases, drops are usually prescribed.
  • Burns, infected wounds, trophic ulcers, consequences of frostbite and other skin damage. Their treatment uses local treatment with a solution and gauze bandages.
  • Prolonged rhinitis, adenoids, bronchial asthma, hay fever and similar diseases. Therapy for such pathologies may include inhalations with Derinat.
  • Radiation damage, resistance to cytostatics, lung diseases, sepsis and other serious pathologies. Such diagnoses require injection of medication.

The solution is indicated as an independent remedy:

  • with acute respiratory infections;
  • for the prevention and treatment of ARVI;
  • for the treatment of inflammatory, purulent-inflammatory and dystrophic ophthalmological diseases;
  • for the treatment of inflammatory diseases of the mucous membranes of the oral cavity.

In combination with other drugs, Derinat is prescribed for the treatment of:

  • chronic inflammatory diseases, as well as bacterial, fungal and other infections in gynecology;
  • diseases of the upper respiratory tract occurring in acute and chronic forms (for example, rhinitis or sinusitis);
  • OZNK;
  • difficult-to-heal and infected wounds, trophic ulcers (including non-healing purulent wounds in diabetes mellitus);
  • gangrene;
  • frostbite, burns;
  • hemorrhoids;
  • necrosis of the skin and mucous membranes provoked by radiation therapy.

Derinat is administered intramuscularly:

  • to stimulate the function of hematopoiesis (hematopoiesis);
  • in the treatment of radiation injuries;
  • in the case of the development of myelodepression (inhibition of the function of bone marrow hematopoiesis) and resistance to cytostatic drugs, which manifests itself in patients with cancer during cytostatic and/or radiation antitumor therapy;
  • for the treatment of stomatitis provoked by cytostatic antitumor therapy;
  • with ischemic heart disease;
  • for stomach ulcers;
  • with duodenal ulcer;
  • with acute neurological disease stages I and II;
  • for the treatment of difficult-to-heal wounds and trophic skin lesions (burns, ulcers, bedsores, etc.);
  • for the treatment of odontogenic sepsis complicated by purulent-resorptive fever;
  • for rheumatoid arthritis;
  • for the treatment of diseases of the urogenital tract caused by the activity of chlamydia, mycoplasmas, ureaplasmas;
  • for burn disease;
  • for prostatitis;
  • with endometritis;
  • for COPD and pulmonary tuberculosis.

As an independent remedy, Derinat injections are also used in surgical practice, prescribed to patients both in the pre- and postoperative period.

Injections and drops of Derinat have no other contraindications, except for the patient’s intolerance to the components included in its composition.

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Directions for use and doses

The drug is prescribed to children from the first day of life and to adults. To prevent ARVI, instill 2 drops into the nose in each nasal passage 2-4 times a day for 1-2 weeks. When symptoms of “colds” appear, the drug is instilled into the nose, 2-3 drops into each nasal passage every 1-1.5 hours, during the first 24 hours; further - 2-3 drops in each nasal passage 3-4 times a day, course duration - 1 month.

For inflammatory diseases of the nasal cavity and paranasal sinuses, the drug is instilled 3-5 drops into each nasal passage 4-6 times a day. Course duration

— 7-15 days.

For diseases of the oral mucosa, rinse with the drug 4-6 times a day (1 bottle 1-2 rinses). The duration of treatment is 5-10 days.

For chronic inflammatory diseases, fungal, bacterial and other infections in gynecology - intravaginal administration with irrigation of the cervix or intravaginal administration of tampons with the drug, 5 ml per procedure, 1-2 times a day, for 10-14 days.

For severe inflammatory and dystrophic processes in ophthalmology, Derinat is instilled into the eyes 2-3 times a day, 1-2 drops, for 14-45 days.

For post-radiation necrosis of the skin and mucous membranes, for long-term non-healing wounds, burns, frostbite, trophic ulcers of various etiologies, gangrene, application bandages (gauze in two layers) are applied to the affected areas with the drug applied to it 3-4 times during the day or treatment is carried out the affected surface with the drug from a nebulizer 4-5 times a day, 10-40 ml (course of treatment - 1-3 months).

Derinat: composition of the drug and its properties

Derinat is an effective immunomodulatory agent
Derinat contains an active component - sodium deoxyribonucleate. Has auxiliary ingredients:

  • Sodium chloride
  • Water for injection

The effectiveness of the drug lies in the following pharmacological actions:

  • stimulates humoral and cellular immunity
  • reduces inflammation
  • reduces the growth and reproduction of pathogenic microorganisms
  • heals ulcers and wounds of various etiologies
  • activates tissue repair and regeneration
  • increases cell resistance during chemotherapy and radiation
  • restores tissue without leaving scars
  • increases resistance to infections
  • removes harmful substances from the lymph, reduces intoxication
  • normalizes hematopoiesis (regulates the number of lymphocytes, leukocytes, platelets, granulocytes)
  • accelerates the healing process for various diseases
  • reduces the risk of nosocomial infection
  • derinat influences the immune system by stimulating T-helper cells and B-lymphocytes

Derinat is quickly metabolized in the human body, distributed through lymphatic vessels and entering tissues and organs. It accumulates most in the brain, lymph nodes, spleen, and thymus. Its smaller amount is in the stomach and liver. The medicine is partially excreted through defecation and urination. Complete removal of the active component from the body occurs after three days.

Derinat is a colorless liquid. Available in 2 forms:

  • Drops for nose and eyes
  • Solution for injection (5 ml ampoules)

Solution for external use (glass bottles of 10 ml and 20 ml, bottles with a spray nozzle, dropper bottles)

Derinat is stored in a dry place, inaccessible to children, away from direct sunlight. The drug, unopened at a temperature of no more than twenty degrees, lasts for five years. Once the bottle is opened, Derinat is recommended to be used within fourteen days.

The solution, used as a local and external remedy, is used in the form of eye drops, nasal drops, rinses, microenemas, applications and irrigations.

The drug is intended for the treatment of children (and it can be prescribed to children from the first day of life) and adult patients.

Treatment with Derinat can be combined with taking other medications in the form of tablets, ointments, and injection solutions.

Instructions for use of Derinat in the form of rinses, applications, irrigations and microenemas

Diseases of the oral mucosa are treated by rinsing with Derinat (one bottle of solution is enough for one or two rinses). The frequency of procedures is from 4 to 6 times a day. They must be done within 5-10 days.

For the treatment of chronic forms of inflammatory and infectious diseases in gynecology, intravaginal administration of the drug with irrigation of the cervix or intravaginal administration of tampons with the drug soaked in a solution are prescribed.

One procedure requires 5 ml of Derinat. The frequency of procedures is 1-2 per day, the course of treatment is from 10 to 14 days.

For hemorrhoids, microenemas into the rectum are indicated. For one procedure, take from 15 to 40 ml of solution. The duration of treatment is from 4 to 10 days.

For ophthalmological diseases accompanied by inflammatory and degenerative processes, Derinat is prescribed to be instilled into the eyes for 14-15 days, 2 or 3 times a day, one or two drops.

In case of necrosis of the skin and mucous membranes caused by irradiation, with difficult-to-heal wounds, trophic ulcers of various origins, frostbite, burns, gangrene, a sterile application bandage should be applied to the affected areas (using gauze folded in two layers) with a solution applied to it.

Applications are made 3-4 times during the day. It is also possible to treat lesions using Derinat in the form of a spray. The drug is sprayed 4 or 5 times a day. A single dose varies from 10 to 40 ml. The duration of treatment is from 1 to 3 months.

Derinat nasal drops: instructions for use

To prevent respiratory viral infections, Derinat nasal drops are instilled into each nasal passage, two at a time, with a frequency of use of 2 to 4 times a day. Duration of treatment is from one to two weeks.

When cold symptoms appear on the first day, it is recommended to instill two or three drops into each nasal passage every hour and a half. Then the treatment is continued by instilling two or three drops into each nasal passage for a month. The frequency of instillations is 3-4 times a day.

Treatment of inflammatory diseases of the paranasal sinuses and nasal cavity involves administering three to five drops into each nasal passage for one to two weeks, 4-6 times a day.

For acute nasal insufficiency, it is recommended to instill one or two drops into each nasal passage 6 times a day for six months.

Derinat injections: instructions for use

The average single dose of Derinat for an adult patient is 5 ml of a 1.5% solution (equivalent to 75 mg). To reduce pain, it is recommended to inject the drug into the muscle over one to two minutes, maintaining intervals of 24-72 hours between injections.

The frequency of injections and the interval between injections depend on the patient’s diagnosis. So, for ischemic disease, 10 injections are prescribed once every 2 or 3 days (every 48-72 hours). For patients with gastric ulcers or duodenal ulcers, 5 injections are recommended with an interval of 48 hours.

For cancer patients - from 3 to 10 injections with an interval of 1-3 days. In andrology (for example, for prostatitis) and in gynecology (for fibroids, salpingitis, etc.) - 10 injections with an interval of 1-3 days .. Patients with tuberculosis - 10-15 injections with an interval of 1-2 days..

For acute inflammatory diseases, it is recommended to give from 3 to 5 injections with an interval of 1-3 days. For inflammatory diseases occurring in a chronic form, give 5 injections every 24 hours, then another 5 injections every 72 hours.

The instructions for use of Derinat for children indicate that the frequency of intramuscular injections of the solution for a child is the same as for an adult patient.

For children under two years of age, the average single dose of a 1.5% solution is 0.5 ml (corresponding to 7.5 mg). For children from 2 to 10 years old, a single dose is determined at the rate of 0.5 ml of solution for each year of life.

Inhalations with Derinat

In the form of inhalations, the drug is prescribed for the treatment of diseases of the respiratory system: tonsillitis, bronchial asthma, hay fever, adenoids, allergies. For inhalation, the solution in ampoules is mixed with saline in a ratio of 1:4 (or 1 ml of Derinat per 4 ml of saline).

The full course of therapy is 10 procedures lasting 5 minutes each. Treatment should be carried out 2 times a day.

Level 4 ATX code matches:

  • Ridostin
  • Roferon A
  • Leukogen
  • Granocyte
  • Genfaxon
  • Estifan
  • Septilin
  • Inferon
  • Neupogen
  • Imudon
  • Lipoferon
  • Laifferon
  • Sodium nucleinate
  • Intron A
  • Betaferon
  • Neupomax
  • Gepon
  • Lavomax
  • Immunokind
  • Grippferon

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Structural analogues of Derinat are the drugs Panagen, Deoxynate, Sodium deoxyribonucleate.

There are a huge number of drugs on the market that have an effect similar to Derinat: Grippferon, Anaferon, Viferon, Orvirem, Oscillococcinum, etc.

Derinat or Grippferon - which is better?

This question often arises for many mothers who are trying to protect their children from influenza and ARVI. The drugs are incomplete analogues, but at the same time they are very similar in therapeutic effect and indications.

The composition and origin of the drugs vary greatly, but biologically active proteins in both Grippferon and Derinat have immunomodulatory, antiviral and anti-inflammatory effects.

Some are inclined to consider Derinat a slightly more effective medicine than Grippferon, it is a stronger immunomodulator and has a wider spectrum of action. This explains the presence of Derinat in a dosage form for intramuscular injection (Grippferon is available only in the form of drops and nasal spray).

It should be remembered, however, that in cases where health is involved, self-medication is unacceptable, and the final decision on prescribing a particular drug is made by the attending physician, because the same drug can act differently on different patients.

The action of the drug is aimed at increasing the activity of immune cells. For this reason, it is often prescribed to children prone to frequent colds.

Research and reviews of Derinat drops for children and Derinat injection solution indicate that both of these dosage forms are well tolerated by children, have virtually no contraindications and rarely cause unwanted side reactions.

This allows the drug to be used to treat children of different ages, including newborns from the first days of life.

To treat upper respiratory tract infections, children are prescribed inhalations with Derinat. Nasal drops for children are indicated as a therapeutic and prophylactic remedy for runny nose, sinusitis, ARVI, influenza, etc.

As a rule, for preventive purposes, 1-3 drops are instilled into each nasal passage. If the drug is used to treat a child, the dose is increased to 3-5 drops. The frequency of administration can be every hour or hour and a half.

If there are problems with the adenoids, a runny nose or sinusitis, the most effective method of treatment with Derinat is tamponing the nasal passages with a cotton swab soaked in the solution with a frequency of procedures 6 times a day.

If a child is susceptible to conjunctivitis and other purulent-inflammatory ophthalmological diseases, the instructions recommend instilling the solution into the conjunctival sac of the affected eye, 1-2 drops three times a day.

Inflammation of the oral mucosa or gums can be relieved by rinsing with Derinat. If the child is too small and does not know how to rinse his mouth, the mucous membrane is treated several times a day with gauze soaked in a solution.

In complex therapy, the solution is often prescribed for the treatment of vulvovaginitis in girls, accompanied by perianal itching and intestinal disorders of helminthiasis, wounds, burns and frostbite.

Injections and drops of Derinat during pregnancy and breastfeeding are prescribed according to vital signs and only in cases where it is not possible to find specific alternative methods for treating the disease.

Conditions for dispensing from pharmacies

Over the counter.

Source: apteka.103.by

  • Derinat drops are introduced into the child’s nasal passages after cleaning them using cotton swabs or an aspirator. If the drug is stored in the refrigerator, then first you need to warm it up a little (hold it in your palms), and only then drip or inject it into the nose.
  • For colds and flu, in the first 2 days of illness, the medicine is used every 1-2 hours. A single dosage will be 2 drops or 1-2 injections. On the third day of illness, the medication begins to be used 3-4 times a day. The dose for one application remains the same, and the duration of treatment is determined individually (until recovery).
  • In the complex treatment of sinusitis, runny nose and other diseases, Derinat is administered 3-5 drops or 1-2 sprays into each nostril. The medicine is used four to six times a day for 7-15 days.
  • Rinsing the mucous membranes of the mouth and throat is carried out 4-6 times a day, using 1/2-1 bottle of drops for one procedure. The duration of treatment is 5-10 days. If a spray is prescribed for such treatment of the mouth or throat, then use 2-3 presses on the sprayer, directing it to the damaged area.
  • Derinat is dripped into the eyes 1-2 drops 2-3 times a day. Ophthalmologists prescribe such therapy for 2-6 weeks.
  • To prevent acute respiratory infections, the medicine is prescribed three or four times for 1-2 weeks, although the medicine can be dripped throughout the cold season. A single dosage is either 2 drops or 1 spray.
  • Gauze for application dressings when treating skin lesions is moistened with the solution 3-4 times a day. If a spray is used, it is sprayed 4-5 times a day until healing.
  • If a child is prescribed inhalations with a nebulizer, then for one procedure use 1-2 ml of Derinat, mixing them with 1-2 ml of saline solution. Inhalation is carried out 2 times a day, and the entire course of such treatment lasts from 5 to 10 days.
  • The drug is prescribed intramuscularly in a single dose of 0.5 ml for children under 2 years of age and 5 ml for children over 10 years of age. If the child is between 2 and 10 years old, the dosage is calculated by multiplying 0.5 ml by the number of years. The course of treatment is up to 5 injections.

Source: www.o-krohe.ru

Interaction with other drugs

Derinat: solution for local and external use

Derinat is prescribed depending on the form in which it is produced.

The drug for intramuscular use is used in complex therapy for the following diseases:

  • stomach ulcer
  • duodenal ulcer
  • erosive gastroduodenitis
  • coronary heart disease
  • severe stomatitis
  • rheumatoid arthritis
  • thrombophlebitis
  • trophic ulcers
  • ischemic leg disease
  • tuberculosis
  • obliterating vascular diseases of the lower extremities
  • obstructive pulmonary diseases in chronic form
  • sepsis

After administering the solution for these diseases, blood supply is restored and contraction of the heart muscle is normalized.

The drug for intramuscular administration is used for diseases of the genitourinary system of an inflammatory nature:

  • Salpingo-oophoritis
  • Endometritis
  • Endometriosis
  • Prostatitis

In some cases, Derinat is prescribed for prostate adenomas and fibroids. Used to treat ureaplasmosis, mycoplasmosis and chlamydia. Intramuscular injections are also used in oncology. In addition to recovery after chemotherapy, the drug increases the effectiveness of many anticancer medications.

Derinat has a wide spectrum of action

Derinat solution for local use is prescribed for the treatment of respiratory diseases of bacterial and viral etiology, inflammatory processes of the oral mucosa, for example, gingivitis, stomatitis, glossitis. It is also prescribed for the local treatment of female inflammatory diseases: cervicitis, vaginitis, vulvitis. Effective Derinat for fungal diseases of the external genitalia.

Indications for the use of external solution are:

  • Haemorrhoids
  • Burns
  • Trophic ulcers
  • Frostbite
  • Gangrene
  • Damage to the skin and mucous membranes due to irradiation
  • Long-healing wounds

In such conditions, Derinat has an analgesic effect. The product is also used during skin grafting. This helps prevent tissue rejection.

This solution is used for inhalation for diseases of the respiratory system:

  • Pneumonia
  • Bronchitis
  • Tuberculosis
  • Bronchial asthma
  • Tracheitis
  • Laryngitis
  • Tonsillitis
  • Pharyngitis

Derinat drops are indicated for otolaryngological diseases such as frontal sinusitis, rhinitis, sinusitis, sinusitis, and adenoiditis. Eye drops are used in ophthalmology to treat degenerative conditions and inflammation of the eyes (blepharitis, conjunctivitis and blepharoconjunctivitis). Nasal drops are in demand for preventive purposes to prevent acute respiratory infections and acute respiratory viral infections.

Derinat in drops

The dosage of the product depends on the form of its release and the age criterion.

Derinat drops. Drops can be used for therapeutic and prophylactic purposes, starting from birth:

  • For preventive purposes of respiratory diseases, the drug must be instilled into the nasal passages, two drops up to four times a day. The course of prophylaxis is no more than 14 days.
  • In case of acute respiratory infections and acute respiratory viral infections, instillation must be carried out according to this scheme. 2-3 drops into the nasal passage every hour and a half on the first day. In the next day - the same dose only three times, or four times a day. Treatment can last from five days to one month.
  • For otolaryngological diseases, the instillation procedure must be done up to six times a day. The dose for one nasal passage is 3-5 drops. The course of therapy is from one to two weeks.
  • Derinat drops in the complex treatment of ophthalmological diseases are instilled into the eyes, a couple of drops 2-3 times a day. The course of treatment is up to 6 weeks.

The duration of therapy depends on the severity of the disease.

Derinat combines well with antipyretic, antibacterial, antiviral and other medications, so it is often prescribed in combination with these drugs to enhance their effect. When used topically, it is important to remember that Derinat is incompatible with fat-containing ointments and hydrogen peroxide.

When applied topically, the drug is not compatible with hydrogen peroxide and fat-based ointments.

The use of the drug in combination with the main therapy increases the therapeutic effect and reduces the duration of treatment. This also makes it possible to reduce the doses of antibiotics and antiviral drugs.

The use of Derinat increases the effectiveness of therapy with antitumor anthracycline antibiotics and cytostatic drugs; the effect of basic therapy prescribed to patients with peptic ulcer is potentiated; The iatrogenicity of drugs prescribed for the treatment of rheumatoid arthritis decreases (up to 50-70%, which is also accompanied by an improvement in a number of complex indicators of disease activity).

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In cases where a surgical infection provokes the development of sepsis, the introduction of Derinat into combination therapy allows:

  • reduce the level of intoxication in the body;
  • increase the activity of the immune system;
  • normalize hematopoietic function;
  • improve the performance of organs involved in removing toxins from the body.

Shelf life of Derinat

Release forms of the antimicrobial and antiviral drug Derinat:

  • Nasal drops: shelf life – 5 years.
  • Spray for topical use: shelf life – 5 years.
  • Solution for local and external use, provided the bottle is intact, shelf life - 5 years, after opening - 14 days.
  • Solution for intramuscular administration: shelf life – 5 years.

Expiration dates are indicated on the bottle packaging.

When the temperature changes, the active substance sodium deoxyribonuleate disintegrates. Depending on the increased or decreased temperature, the chemical process slows down or accelerates. The shelf life is reduced to 3 days.

Polidexa can be used 5-10 days before the expiration date, provided the vial is intact and properly stored.

After the expiration date, Derinat begins to evaporate.

Signs of a low-quality product:

  • chips and dents on the bottle;
  • poor quality text printing;
  • no expiration dates;
  • discrepancy between the shelf life on the cardboard packaging and the bottle;
  • cloudy heterogeneous solution;
  • presence of sediment;
  • unpleasant smell.

After the expiration date, the drug cannot be used. It may cause a severe allergic reaction.

The long shelf life of Derinat is due to the slow disintegration of the active substance.

Derinat during pregnancy and lactation

Only a doctor can prescribe the use of Derinat depending on the severity of the disease and the risk to the fetus

Before using Derinat to treat pregnant and nursing mothers, the patient should consult a specialist. To prescribe this drug, the doctor must take into account the benefits for the mother and the possible risks for the child.

This is explained by the fact that the use of Derinat has not been studied during pregnancy. That is why the instructions for using the drug insist on the need for individual consultation with a specialist. In addition, it is important for pregnant women to remember that any use of medications in the first trimester can negatively affect the formation of the fetus.

You can put drops in your nose and eyes during pregnancy and breastfeeding. However, it is not advisable to administer the injection solution to pregnant women and nursing mothers.

How to store Derinat at home

In any form, the antiviral drug Derinata should be stored at a temperature of +4 ... + 20 ° C in a dark place.

The best place to store the medicine is in a special compartment in the refrigerator door. Derinat should not be poured into another container. This may lead to damage to the drug. The date the medicine was opened should be indicated on the packaging.

Worst storage places:

  • freezer and general chamber;
  • near heating devices;
  • near food;
  • in the field of view of children;
  • on the balcony and in the storage room.

Analogues of Derinat:

  • Arbidol;
  • Grippferon;
  • Interferon;
  • Viferon;
  • Kagocel;
  • IRS-19;
  • Poludan;
  • Ingavirin.

Archives: Frequently Asked Questions

Two weeks ago I was treated for ARVI. I was discharged to work, but I feel weak, get tired quickly and sweat. What is this connected with? Tell me, what can I do to treat it?

Good afternoon After suffering viral respiratory infections, the so-called asthenovegetative syndrome remains, which causes the symptoms you described. At the same time, the immune system, which is the body’s defense system against harmful factors, also suffers. During this period, a gentle regime and conditions are necessary that promote rapid recovery of the body - dosed exercise and rest, strict adherence to sleep and wakefulness. It is advisable to take multivitamins and restore the immune system. In this case, the drug Derinat in the form of a 0.25% solution for external use is useful. Take 2 drops in each nasal passage 3-4 times a day for 3-4 weeks.

A month ago I had a cold. I took medication and after a week I was healthy, but now I got sick again, and at the appointment the doctor diagnosed ARVI and, along with the usual treatment - antibiotics, painkillers, prescribed me Derinat drops. Is it worth taking it, since only antibiotics helped me well before?

Hello! Derinat is a multi-acting drug. It belongs to drugs that restore immunity, enhances the effect of other drugs, and relieves toxic manifestations of both the disease and the medications taken. In addition, you have a decrease in the body's defenses, most likely this is due to a weakened immune system, which should protect the body from various harmful factors. The drug Derinat will help you solve all these problems. Take 2-3 drops of a 0.25% solution of Derinat intranasally (in each nasal passage) 3-4 times a day for 3-4 weeks.

The child is 5 years old, has atopic dermatitis, recurrent aphthous stomatitis, and now has urticaria. The doctor recommended a one-time injection of Derinat 5 ml, I am afraid to give the injection, since allergies are clearly present in the form of cough and hives. I'm asking for advice

Hello, the doctor prescribes treatment for you based on the clinical picture of the disease, and if he had doubts about this therapy, he would not use Derinat. But if you have doubts, try using the local form of Derinat in the form of a 0.25% rinse solution to treat aphthous stomatitis, first making sure that the child tolerates Derinat well.

Hello, after what period of time can Derinat be instilled into a 10-month-old child with a runny nose (we already instilled it a month ago and it helped us).

Hello! You can safely instill Derinat into your baby if the need for it arises (for example, if you have a runny nose), because the drug is absolutely harmless and does not lose its effectiveness with frequent use. However, I would advise you to examine your child to establish the causes of his frequent illness (take a bacterial culture of swabs from the mucous membranes of the upper respiratory tract for the presence of pathogenic microflora, a stool test to study the repertoire of intestinal microflora and a blood test to exclude congenital defects of the immune system), because . More serious problems may be hidden under the mask of frequent ARVI.

A child goes to kindergarten. Is it possible to use derinat for prevention so that he does not pick up any sores?

Good afternoon!! Yes, of course, Derinat 0.25% solution is indicated for the prevention of colds in children. A number of clinical trials have been conducted that have proven the effectiveness of Derinat not only for prevention, but also for the treatment of influenza and colds.

A frequently ill child, 4 years old, adenoids removed a year ago. Derinat was prescribed in injections - 5 injections according to the scheme, 5 ml per single dose... Isn't this too high a dose for this age?

Alena, good afternoon!! According to the instructions, a single dose of Derinat 15 mg/ml in children from 2 to 10 years is determined at the rate of 0.5 ml per year of life. That is, in your case it is 2 ml. If the doctor prescribed 5 ml for your child, you need to clarify the prescription regimen again. Perhaps the doctor had special reasons for this.

Hello. My daughter is 7 months old, she recently got sick with an acute respiratory infection, she still has a runny nose, and only oxolinic ointment was put in her nose (pediatrician’s advice). Is it possible to use Derinat at this age, and is it necessary to rinse the nose first?

Galina, good afternoon!! Derinat is approved for use in children from the 1st day of life. Before use, first clear mucus from the child’s nasal passages.

Hello! The child is 2.5 years old. He goes to kindergarten, but often catches colds or suffers from viral diseases. Often it is necessary to resort to treatment with antibiotics. Will your drug help in this case? Thank you.

Vladimir, good afternoon!! Since the child belongs to the group of frequently ill children, he needs to use Derinat not only to treat the disease that has arisen, but also for preventive purposes in order to reduce the frequency and duration of colds and prevent the development of complications. In this regard, leading pediatricians who studied the effect of Derinat on a group of frequently ill children recommended the following regimen: before the start and directly during the epidemic season, use Derinat 2 drops in each nasal passage 2 times a day for 2 to 3 months.

My child is 1.8 months old, he was diagnosed with ARVI, he was prescribed Derinat nasal drops, I have been giving them to him for 2 weeks now, there is an improvement, but he still has a runny nose. Please tell me how long can these drops be used?

Alexandra, good afternoon!! Derinat 0.25% solution for local and external use can be used for a child for up to 1 month. Regarding the advisability of use, contact your treating pediatrician.

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Good evening! My 7-month-old daughter has one eye festering (not too much), the doctors said she needs to pierce the tear duct. I do a massage, apply ointment, but to no avail. But will derinat help me?

Love, good afternoon!! Derinat is used in ophthalmology for inflammatory diseases, but, nevertheless, you need to once again consult with your doctor about the advisability and regimen of using the drug Derinat.

Hello, after what period of time can Derinat be instilled into a 10-month-old child with a runny nose (we already instilled it a month ago and it helped us).

Reviews of Derinat nasal drops

Like all immunomodulatory drugs, Derinat activates and stimulates immune defense mechanisms. However, it does not fight the infection directly. For this reason, in many cases people describe the drug as ineffective. Indeed, if a person has a progressive respiratory disease, then instilling Derinat will not bring any visible benefit. For example, judging by the reviews, the effectiveness of its use in the inflammatory process in the sinuses is low.

Reviews of the preventive use of Derinat drops note a decrease in the incidence of acute respiratory viral infections, as well as exacerbations of chronic pharyngitis, tonsillitis, rhinitis, and sinusitis.

Some reviews note rare cases of individual intolerance to medicinal drops. An allergic reaction to the drug is possible.

Reviews of Derinat for children

Mothers whose children often catch colds and also have enlarged adenoids note that pediatricians in most cases prescribe Derinat drops to the child. Reviews about the preventive use of the drug are positive. By increasing resistance to microbes accumulating in the nasopharynx, it is possible to:

  • reduce the number of inflammatory relapses and episodes of acute respiratory viral infections;
  • significantly improve the condition of the child’s nasopharyngeal mucosa.

Caution should be exercised when using Derinat in children with food allergies.

Reviews of Derinat for infants

There have been no negative reviews about the use of Derinat drops in infants. In some cases, for example, for bottle-fed children and premature babies, doctors recommend using the drug at the slightest runny nose.

Reviews note that Derinat is well tolerated by infants, as well as the absence of any adverse reactions.

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